Nanopore Sequencing: From Imagination to Reality
نویسندگان
چکیده
منابع مشابه
Nanopore sequencing: from imagination to reality.
DNA sequencing and hence genomics have been transformed over the last decade by the commercialization of inexpensive, massively parallel, short-read sequencing technology. Nonetheless, a new generation of singlemolecule DNA sequencers, which uses nanopore technology, is initiating a further upheaval in genomics. These instruments are portable, capable of reads of 100 kb, cheap, and fast. Nanopo...
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Children engage with their imaginative faculties in a variety of ways as they grow and develop. Th ey play simple pretend games starting at about the age of two (Fein, 1981; Nicolich, 1977; Singer & Singer, 1990), which are then elaborated into longer pretend sequences and sometimes into ongoing relationships with imaginary companions (Taylor, 1999) and paracosms (see chapter 27). Children also...
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A single molecule of Deoxyribonucleic acid (DNA) is being sequenced by using an innovative concept of Nanopore. The orientation of nanopore define the channel of ions through the pore comes into contact with nucleotide, the permutation and the transition kinematics of each molecule of DNA. The divergence of electrical signal observed when the four chemical bases adenine (A), guanine (G), cytosi...
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The "$1000 Genome" project has been drawing increasing attention since its launch a decade ago. Nanopore sequencing, the third-generation, is believed to be one of the most promising sequencing technologies to reach four gold standards set for the "$1000 Genome" while the second-generation sequencing technologies are bringing about a revolution in life sciences, particularly in genome sequencin...
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Received 6 January 2015; accepted 5 November 2015; published online 6 May 2016; doi:10.1038/nbt.3423 and together with Sergey Bezrukov at the US National Institutes of Health (NIH), had established the conditions that were necessary to avoid spontaneous gating (pore closure) of the a-hemolysin channel3. This was important, because spontaneous gating would have hindered, or confused, observation...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2015
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2014.223016